Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Combining indocyanine green fluorescence imaging and ultrasound intraoperatively to visualize primary and secondary cancerous lesions in the liver: Systematic review and meta-analysis.

Surgery·2026
Same author

Nfkb1 is a haploinsufficient DNA damage-specific tumor suppressor.

Oncogene·2014
Same author

Oral cavity tumors in younger patients show a poor prognosis and do not contain viral RNA.

Oral oncology·2013
Same author

The diagnosis and management of Piriformis Syndrome: myths and facts.

The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques·2012
Same author

A vision for a biomedical cloud.

Journal of internal medicine·2011
Same author

Capturing genomic signatures of DNA sequence variation using a standard anonymous microarray platform.

Nucleic acids research·2006

相关实验视频

Updated: Jun 27, 2026

A Rapid and Efficient Method to Dissect Pupal Wings of Drosophila Suitable for Immunodetections or PCR Assays
07:11

A Rapid and Efficient Method to Dissect Pupal Wings of Drosophila Suitable for Immunodetections or PCR Assays

Published on: December 30, 2017

在变形过程中对Drosophila发育的微阵列分析.

K P White1, S A Rifkin, P Hurban

  • 1Department of Developmental Biology, Beckman Center B300, Stanford University School of Medicine, Stanford, CA 94305-5329, USA.

Science (New York, N.Y.)
|December 11, 1999
PubMed
概括

研究人员使用DNA微阵列识别了数千个参与果变形的基因. 这项研究揭示了对这种复杂的发育过程至关重要的新基因功能和途径.

科学领域:

  • 发育生物学是发展生物学.
  • 基因组学就是基因组学.
  • 分子生物学分子生物学

背景情况:

  • 变形是一个复杂的发育过程,涉及复杂的基因调节.
  • 了解转变的遗传基础对于发育生物学至关重要.

研究的目的:

  • 在果变形过程中识别和分析基因表达.
  • 发现参与这种发育转变的新基因和途径.

主要方法:

  • 构建高密度DNA微阵列,其中包含数千个Drosophila melanogaster基因序列.
  • 对基因表达模式的分析,以确定差异表达的基因.

主要成果:

  • 在转化过程中确定了许多差异表达的基因.
  • 将许多基因分配给已知的发育途径,并发现了新的关联.
  • 发现了许多具有以前未知的功能,可能调节变形的基因.

结论:

  • 基于基因组的方法,如DNA微阵列,是研究复杂生物过程的强大工具.
  • 这项研究为了解果变形提供了全面的遗传资源,并为研究确定了新的途径.

更多相关视频

Imaging and Analysis of Tissue Orientation and Growth Dynamics in the Developing Drosophila Epithelia During Pupal Stages
08:25

Imaging and Analysis of Tissue Orientation and Growth Dynamics in the Developing Drosophila Epithelia During Pupal Stages

Published on: June 2, 2020

Analysis of Cell Differentiation, Morphogenesis, and Patterning During Chicken Embryogenesis Using the Soaked-Bead Assay
06:49

Analysis of Cell Differentiation, Morphogenesis, and Patterning During Chicken Embryogenesis Using the Soaked-Bead Assay

Published on: January 12, 2022

相关实验视频

Last Updated: Jun 27, 2026

A Rapid and Efficient Method to Dissect Pupal Wings of Drosophila Suitable for Immunodetections or PCR Assays
07:11

A Rapid and Efficient Method to Dissect Pupal Wings of Drosophila Suitable for Immunodetections or PCR Assays

Published on: December 30, 2017

Imaging and Analysis of Tissue Orientation and Growth Dynamics in the Developing Drosophila Epithelia During Pupal Stages
08:25

Imaging and Analysis of Tissue Orientation and Growth Dynamics in the Developing Drosophila Epithelia During Pupal Stages

Published on: June 2, 2020

Analysis of Cell Differentiation, Morphogenesis, and Patterning During Chicken Embryogenesis Using the Soaked-Bead Assay
06:49

Analysis of Cell Differentiation, Morphogenesis, and Patterning During Chicken Embryogenesis Using the Soaked-Bead Assay

Published on: January 12, 2022