心率和肌肉交感神经活动对血压的交互作用
1Cardiovascular Neurophysiology Laboratory, Cardiovascular Division, Department of Internal Medicine, University of Iowa, Iowa City, USA.
Circulation
|December 22, 1999
概括
肌肉交感神经活动 (MSNA) 和心率相互作用,影响正常压力男性的血压. 较高的MSNA与高血压有关,但仅在心率较快的男性中.
科学领域:
- 心血管生理学心血管生理学
- 自主神经系统的调节规则
背景情况:
- 交感神经系统通过血管和心脏影响影响血压.
- 肌肉交感神经活动 (MSNA) 和血压调节之间的长期关系尚不清楚.
- 快速的心率通常与更高的血压有关.
研究的目的:
- 为了调查MSNA和心率与正常压力个体的血压水平相关的假设.
- 探索MSNA,心率和血压调节之间的潜在相互作用.
主要方法:
- 研究包括120名男性和48名女性正常压力受试者.
- 参与者根据心率和MSNA分布被分为三分之一.
- 在这些三角动物中分析了血压 (心压,腹压,脉).
主要成果:
- 在男性中,血压在心率三分之一之间有显著的变化,在上三分之一中压力最高.
- 在MSNA三角动物中没有发现血压的直接显著差异.
- 观察到一种相互作用:较高的MSNA与较高的缩压和脉冲压相关,仅在最高心率三位数内的男性中.
- 在女性受试者中,没有发现心率,MSNA和血压之间的显著关联.
结论:
- MSNA和心率相互作用,在正常血压的男性中影响缩和脉冲压.
- 在心率较慢的个体中,MSNA和血压之间没有明显的关系.
- 在心率较快的男性中,高的MSNA与缩和脉冲压的增加有关.
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