根据肠乳的血清度,急性冠状动脉事件的风险:基于人口的前性病例控制研究
M Vanharanta1, S Voutilainen, T A Lakka
1Research Institute of Public Health, University of Kuopio, Finland.
Lancet (London, England)
|December 28, 1999
概括
在男性中,高血清肠乳水平与急性冠状动脉事件的风险降低有关. 这表明,富含植物的饮食可以预防心脏病.
科学领域:
- 心血管健康 心血管健康
- 营养流行病学 营养流行病学
- 微生物组研究 微生物组研究
背景情况:
- 肠道微生物群所产生的灵类物质,因其潜在的抗癌作用而受到研究.
- 肠乳对心血管疾病风险,特别是急性冠状动脉事件的作用尚未得到充分证实.
研究的目的:
- 调查血清中肠乳的度与急性冠状动脉事件的风险之间的关联.
- 在中年男性中探讨肠乳的潜在心脏保护作用.
主要方法:
- 一项前性嵌套病例控制研究对2005年中年男性进行.
- 使用时间解析免疫检测测法测量血清肠乳.
- 167名患有急性冠状动脉事件 (病例) 的男性与167名没有冠状动脉心脏病的对照进行了匹配.
主要成果:
- 平均血清肠乳在病例中 (18.2 nmol/L) 比对照组 (23.5 nmol/L) 低.
- 肠乳四分之一最高的男性 (>30.1 nmol/L) 患急性冠状动作风险降低了58.8%.
- 在调整了主要心血管风险因素后,这种风险降低持续在65.3%.
结论:
- 在健康男性中,较高的血清肠乳度与急性冠状动脉事件的风险降低有关.
- 研究结果支持这样一个假设:富含植物性,纤维丰富食物的饮食可能会降低冠状动脉疾病的风险.
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