NIH-3T3细胞的stat3介导转化由构成性活性的Q205L Galphao蛋白进行

P T Ram1, C M Horvath, R Iyengar

  • 1Department of Pharmacology, Immunobiology Center, Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, NY 10029, USA. ramp01@doc.mssm.edu

Science (New York, N.Y.)
|December 30, 1999
PubMed
概括

在NIH-3T3细胞中表达非GTPase活性的Galphao亚单元诱导了细胞转化,并通过c-Src激酶活性激活了信号转换器和转录3 (Stat3) 的激活器.

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