概括
甲基酸可以导致儿童出现或恶化,影响1.3%的患者. 这些罕见的副作用可能表明某些人格类型的敏感性.
科学领域:
- 儿科神经学 儿科神经学
- 儿童精神病学 儿童精神病学
- 药理学 药理学是指药理学的学科.
背景情况:
- 甲基化是一种常见的兴奋剂药物,用于治疗儿童注意力缺陷多动症 (ADHD) 和其他疾病.
- 触动是非自愿的,突然的,快速的,反复的,非节律的运动运动或发声.
研究的目的:
- 为了研究使用甲基酸治疗的儿童中发作或恶化的发作和特征.
- 探索可能的风险因素或与甲基胺诱导的结相关的患者个人资料.
主要方法:
- 对于在甲基酸治疗期间出现滴答的儿童的医疗记录的回顾性分析.
- 收集关于患者人口统计,诊断 (最小脑功能障碍,吉尔德·德·劳雷特综合征),药物剂量,持续时间和的表现的数据.
主要成果:
- 在14名儿童中出现了,在6名儿童中恶化了先前存在的,占研究人群的1.3% (1,520人中20人).
- 在发育和药物剂量或持续时间之间没有明确的相关性.
- 大多数情况下,在停止治疗后,会消失,只有一个病例显示持续性.
结论:
- 甲基胺诱导的是罕见的,但可以发生在儿童身上,这表明潜在的潜在易感性.
- 观察到的个性特征 (痴迷,坚持不,收缩) 可能与这种易感性有关.
- 需要进一步的研究来阐明机制,并确定甲基酸相关的滴答障碍的预测因素.
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