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相关实验视频

Updated: Jul 12, 2026

Milk Collection in the Rat Using Capillary Tubes and Estimation of Milk Fat Content by Creamatocrit
07:38

Milk Collection in the Rat Using Capillary Tubes and Estimation of Milk Fat Content by Creamatocrit

Published on: December 16, 2015

长链多不和脂肪酸补充婴儿配方奶的有效性和安全性:一项随机试验.

A Lucas1, M Stafford, R Morley

  • 1MRC Childhood Nutrition Research Centre, London, UK.

Lancet (London, England)
|January 6, 2000
PubMed
概括

将长链多不和脂肪酸 (LCPUFA) 添加到婴儿配方奶粉并没有改善婴儿的认知或运动发育. 没有观察到任何不良影响,但该研究不支持在标准婴儿配方中补充LCPUFA.

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科学领域:

  • 儿童营养学 儿童营养学
  • 神经发育儿科 神经发育儿科
  • 临床试验 临床试验

背景情况:

  • 婴儿配方奶粉通常缺乏必需的长链多不和脂肪酸 (LCPUFA).
  • LCPUFA对于婴儿的认知和运动发育至关重要.
  • 配方中LCPUFA补充剂对长期发育的影响尚未完全理解.

研究的目的:

  • 为了评估添加n-3和n-6LCPUFA到婴儿配方奶粉的效果.
  • 评估对长达18个月的认知和运动发育的影响.
  • 为了确定LCPUFA补充剂的任何不良后果.

主要方法:

  • 一项双盲,随机,受控试验与447名健康婴儿进行.
  • 婴儿接受了配有或不配有LCPUFA的配方奶粉,或是母乳养 (参考组).
  • 使用贝利尺度和Knobloch,Passamanick和Sherrards测试来评估认知和运动发育;安全结果包括感染,和生长.

主要成果:

  • 在配方组之间没有发现认知 (MDI) 或运动 (PDI) 发育的显著差异.
  • 成长,感染率,亚托皮和胃肠道耐受性在各组中都相似.
  • 配方奶粉养的婴儿在经过调整后,与母乳养的参考组的发育得分相似.

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Last Updated: Jul 12, 2026

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Published on: December 16, 2015

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结论:

  • 在婴儿配方中补充LCPUFA,对长达18个月的发育或生长没有有益或有害影响.
  • 虽然没有发现安全问题,但未来的试验应该收集详细的安全数据.
  • 目前的证据不支持将LCPUFA添加到标准婴儿配方奶粉中.