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Updated: Jul 20, 2026

Using X-ray Crystallography, Biophysics, and Functional Assays to Determine the Mechanisms Governing T-cell Receptor Recognition of Cancer Antigens
09:53

Using X-ray Crystallography, Biophysics, and Functional Assays to Determine the Mechanisms Governing T-cell Receptor Recognition of Cancer Antigens

Published on: February 6, 2017

一个 gamma delta T 细胞受体连接体 T22 的晶体结构:一个截断的 MHC 类折叠

C Wingren1, M P Crowley, M Degano

  • 1Department of Molecular Biology and the Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

Science (New York, N.Y.)
|January 15, 2000
PubMed
概括

鼠T10和T22,相关的非经典MHC Ib蛋白质,直接与马达尔塔T细胞受体结合. 结构分析揭示了一种不寻常的MHC类折叠,表明了明显的gammadelta和alphabeta T细胞受体相互作用.

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