左心室透静性质与动脉高血压中静脉功能之间的关系
G de Simone1, R Greco, G Mureddu
1Department of Clinical and Experimental Medicine, Federico II University Hospital, Naples, Italy. simogi@unina.it
Circulation
|January 19, 2000
概括
在高血压中,扩张性功能障碍可能会在收缩性功能障碍之前出现. 中壁缩短 (MS) 障碍与左心室 (LV) 放松延迟有关,即使射出分数 (EF) 正常.
科学领域:
- 心脏病学 心脏病学
- 心血管生理学心血管生理学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
背景情况:
- 左心室 (LV) 舒张功能障碍在高血压中很常见.
- 在高血压患者中,腹功能障碍和心功能之间的关系尚未完全理解.
研究的目的:
- 调查左心室 (LV) 透缩功能障碍是否独立于高血压患者的系统功能障碍.
- 为了确定中壁缩短 (MS) 与高血压中同体体松时间 (IVRT) 之间的关联.
主要方法:
- 多普勒心声学被用于研究159名高血压患者和165名正常血压对照.
- 测量了射出分数 (EF),中壁缩短 (MS),同体体松时间 (IVRT) 和减速时间.
- 进行了多变量分析,以评估独立的关系.
主要成果:
- 与正常血压患者相比,高血压患者的EF较高,但MS较低,即使在调整后也是如此.
- 异体放松时间 (IVRT) 和减速时间在高血压患者中明显较长.
- IVRT与受损的MS独立相关,而不是EF,即使控制了LV几何和负载,IVRT仍然很高.
结论:
- 在高血压中存在延迟LV放松的多普勒指数,独立于缩功能.
- 损伤的中壁缩短 (MS) 独立地与延迟的LV放松有关.
- 扩张性异常可以先于收缩性功能障碍,即使在中间壁水平测量时也是如此.
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