针对临床局部性前列腺癌的激进前列腺切除术后尿路和性功能:前列腺癌结果研究
J L Stanford1, Z Feng, A S Hamilton
1Fred Hutchinson Cancer Research Center, Department of Epidemiology, University of Washington, Seattle 98109-1024, USA. jstanfor@fhcrc.org
JAMA
|January 27, 2000
概括
针对前列腺癌的激进前列腺切除术显著影响性功能,近60%的男性经历了阳,超过40%的人报告了性表现问题. 泌尿功能也会下降,这突显出需要对治疗并发症进行明智的患者-医生讨论.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 在瘤学瘤学.
- 公共卫生 公共卫生
背景情况:
- 在基于人口的队列中,关于前列腺切除并发症的数据有限.
- 医生和患者需要有关治疗结果的全面信息.
研究的目的:
- 为了评估局部前列腺癌的激进前列腺切除术后尿路和性功能的变化.
- 在多样化的患者群体中提供有关功能结果的数据.
主要方法:
- 基于人口的纵向队列研究 (前列腺癌结局研究).
- 在诊断后的24个月内,对1291名男性进行了随访.
- 在基线和6,12和24个月时评估尿路和性功能.
主要成果:
- 在手术后18个多月,8.4%的患者患有失禁,59.9%患有阳.
- 阳率因神经节约技术而异 (56.0%-65.6%).
- 性功能因年龄和种族而异;尿功能因年龄而异.
结论:
- 根本性前列腺切除与严重的勃起功能障碍和一些尿功能下降有关.
- 这些研究结果为医生和患者提供了关键的见解,帮助他们进行前列腺癌治疗选择.
- 年龄和种族是影响前列腺切除术后性和泌尿功能的重要因素.
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