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克隆和异质表达epothilone基因集群的克隆和异质表达

L Tang1, S Shah, L Chung

  • 1KOSAN Biosciences, 3832 Bay Center Place, Hayward, CA 94545, USA.

Science (New York, N.Y.)
|January 29, 2000
PubMed
概括

科学家们克隆了来自Sorangium cellulosum的epothilone基因集群,并将其表达在Streptomyces coelicolor中. 这使得能够产生潜在的抗癌药物epothilones A和B,供应丰富.

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