呼吸道病毒感染对患有慢性潜在疾病的人的影响
W P Glezen1, S B Greenberg, R L Atmar
1Department of Microbiology and Immunology, Baylor College of Medicine, Houston, Tex 77030, USA. wglezen@bcm.tmc.edu
呼吸道病毒感染经常使慢性病患者住院. 流感,偏流感和呼吸道同胞病毒 (RSV) 是常见的罪祸首,强调需要新疫苗.
科学领域:
- 传染性疾病 传染性疾病
- 肺部病理学 肺部病理学
- 流行病学 流行病学
背景情况:
- 自1980年以来,急性下呼吸道感染的住院病例有所增加.
- 了解感染原因对于预防脆弱患者的呼吸道疾病至关重要.
研究的目的:
- 在慢性病患者中确定导致住院治疗的特定病毒感染的频率.
- 分析急性呼吸道疾病的病毒病因.
主要方法:
- 分析了急性呼吸道疾病住院的1029名患者的病毒病因 (1991年7月至1995年6月).
- 利用病毒培养,抗原检测和抗体升进行诊断.
- 根据收入状况比较住院率.
主要成果:
- 在可用样本的44.9%的患者中检测到呼吸道病毒感染.
- 在检测到的病毒感染中,流感,副流感和呼吸道同胞病毒 (RSV) 占了75%.
- 患有慢性肺病的低收入患者的住院率比中等收入患者高8倍.
结论:
- 呼吸道病毒感染是严重急性呼吸道疾病的常见触发因素,在患有慢性疾病的患者中需要住院治疗.
- 强调迫切需要针对这些病毒,特别是偏流感和RSV的有效疫苗.
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