草药与药物的相互作用
1George Washington University School of Medicine and Health Sciences, Department of Health Care Sciences, Washington, DC 20037, USA. fughberman@aol.com
Lancet (London, England)
|February 16, 2000
概括
同时使用草药和药物可以导致危险的相互作用. 医疗保健提供者应建议患者避免混合草药和药物,因为可能会产生不良影响.
科学领域:
- 药理学 药理学是指药理学的学科.
- 综合医学是一个整体的医学.
- 草药是一种草药.
背景情况:
- 同时使用草药产品和药物是常见的.
- 草药可以与药物相互作用,改变它们的疗效和安全性.
- 了解这些草药相互作用对于患者护理至关重要.
研究的目的:
- 审查和总结有关草药相互作用的记录案例.
- 为了突出结合草药和制药产品产生的潜在不良影响.
- 强调关于草药使用的临床意识和患者咨询的重要性.
主要方法:
- 关于已报告的草药相互作用的文献综述.
- 特定草药及其相互作用的药剂的识别.
- 根据临床结果对相互作用进行分类 (例如,出血,血综合征,生物可用性变化).
主要成果:
- 同时使用华法林和银杏,大,东或丹申可能会增加出血风险.
- 圣约翰草可以引起SSRI的轻度血清激素综合征,并降低迪戈辛,神菲林,环素和phenprocoumon的生物可用性.
- 帕纳克斯人参可能会在服用抗抑郁药的患者中诱发躁狂;贝特尔坚果可以加剧神经乱药的外皮拉米德效应.
- 约欣宾可能会增加三环抗抑郁药的高血压风险;甘露可以增强皮质类固醇.
- 一些中国和阿育吠陀的药物可以降低特定药物的血度.
结论:
- 草药相互作用带来重大风险,从药物的疗效改变到严重的不良事件.
- 许多报告的相互作用缺乏详细的分析,需要谨慎的解释.
- 医疗保健从业人员必须主动地向患者提供建议,说明将草本产品与处方药或非处方药结合使用的潜在危险.
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