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Updated: Aug 13, 2026

Two-photon Imaging of Intracellular Ca2+ Handling and Nitric Oxide Production in Endothelial and Smooth Muscle Cells of an Isolated Rat Aorta
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在过度表达内皮氧化合成酶的转基因小鼠中对内毒素冲击的耐药性

T Yamashita1, S Kawashima, Y Ohashi

  • 1First Department of Internal Medicine, Kobe University School of Medicine, Kobe, Japan.

Circulation
|March 1, 2000
PubMed
概括

过度表达内皮氧化合成酶 (eNOS) 保护小鼠免受感染性休克. 这通过减少低血压,肺损伤和由脂多糖 (LPS) 引起的炎症来提高生存率.

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相关概念视频

Enzyme Inhibition01:30

Enzyme Inhibition

Inhibitors are molecules that reduce enzyme activity by binding to the enzyme. In a normally functioning cell, enzymes are regulated by a variety of inhibitors. Drugs and other toxins can also inhibit enzymes. Some inhibitors bind to the enzyme’s active site, while others inhibit enzymatic activity by binding to other sites on the protein structure.