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靠近心房结束,心房结节和远距离心房结束是具有独特组织学特征和内化特征的独特解剖结构
1Department of Medicine, Cardiology, The Feinberg Cardiovascular Research Institute, Northwestern University, Chicago, IL, USA.
Circulation
|March 7, 2000
概括
心房节点 (AVN) 和相关捆绑 (PAVB,DAVB) 具有独特的组织学特征,证实了它们在心脏导电中的特殊作用. 这些独特的特征将AV结与普通心肌隔离开来.
科学领域:
- 心血管组织学心血管组织学
- 心脏电生理学 心脏电生理学
- 肌肉心脏的超结构.
背景情况:
- 直接的3D分析显示,心房节点 (AVN) 连接到近端 (PAVB) 和远端 (DAVB) AV捆的专门心肌.
- 解剖学连续性表明心脏导电系统内有一个专门的功能.
研究的目的:
- 为了在组织学上区分近端AV捆绑 (PAVB),心房结节 (AVN) 和远端AV捆绑 (DAVB).
- 为了比较这些专业组织与普通心肌.
主要方法:
- 采用了一种保护组织完整性的协议,用于3个直角平面的连续切口.
- 使用立体毒性分析检查了AV结区域.
主要成果:
- PAVB,AVN和DAVB的特点是聚合的肌纤维在有着明显的螺旋和原组织的束状.
- 带的方向有所不同:在PAVB和DAVB中平行,在AVN中交织在一起.
- 肌细胞表现出独特的周核区域,末端过程,交叉纹和间隙盘,在PAVB,AVN和DAVB之间有所不同.
结论:
- PAVB,AVN和DAVB具有独特的组织学特征,使其与普通心肌有所区别.
- 原隔离形成了自然障碍,在解剖学上隔离了AV接口.
- 这些发现证实了AV连接作为一个专门的心脏导电系统.
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