埃诺西蒙回声心脏学用于预测复苏后的左心室功能障碍的恢复:检测心肌活力的新测试
1Department of Cardiovascular Sciences, Istituto Scientifico/Università San Raffaele, Milan, Italy. lu.chunzeng@hsr.it
Circulation
|March 22, 2000
概括
埃诺西蒙回声心脏学有效预测心肌复苏后再血管化,显示较高的灵敏度和较少的血动力学效应比多布胺回声心脏学为冠状动脉疾病患者.
科学领域:
- 心脏病学 心脏病学
- 诊断成像 诊断成像 诊断成像
- 药理学 药理学是指药理学的学科.
背景情况:
- 评估心肌功能障碍的复苏后的重血管化是至关重要的.
- 埃诺西蒙 (一种阳性无otropic 剂) 与心声回声学结合用于这种恢复的预测能力仍然未被评估.
研究的目的:
- 评价埃诺西蒙回声心脏学在重血管化后预测左心室功能障碍的功能恢复的能力.
- 为了比较其有效性和安全性与多布他胺心声学.
主要方法:
- 45名患有冠状动脉疾病和左心室功能障碍的患者接受了多布他胺 (DE) 和埃诺西蒙 (EE) 声心成像.
- 心肌壁运动得到了评分,改善被定义为至少一个等级的下降.
- 评估了重血管化后的功能恢复,并与心声回声学发现相关联.
主要成果:
- 与多布胺心声学 (DE) 相比,因诺西蒙心声学 (EE) 在预测功能恢复方面表现出更高的灵敏度 (88%) 和负预测值 (90%).
- 两种方法都显示出相似的特异性和积极的预测值;在85%的细分段中观察到一致性.
- 供应只用EE改善的区域的血管比对两种药物的反应 (77.7%) 有显著更大的狭窄 (89.9%).
结论:
- 埃诺西蒙心声学提供了一种可靠的方法,用于预测心肌复苏后心肌功能恢复.
- 它表现出优越的灵敏度,并诱导较少显著的血液动力学变化 (例如,血压变化) 与多布胺心声相比.
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