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Updated: Jul 5, 2026

Recombineering Homologous Recombination Constructs in Drosophila
14:23

Recombineering Homologous Recombination Constructs in Drosophila

Published on: July 13, 2013

一个Drosophila互补的DNA资源

G M Rubin1, L Hong, P Brokstein

  • 1Berkeley Drosophila Genome Project, Howard Hughes Medical Institute, and Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720-3200, USA.

Science (New York, N.Y.)
|March 24, 2000
PubMed
概括

研究人员制定了一种策略,以创建互补的DNA (cDNA) 克隆集合. 这种方法已经确定了果Drosophila melanogaster中40%以上的基因,有助于基因研究.

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相关概念视频

Exon Recombination02:32

Exon Recombination

The evolution of new genes is critical for speciation. Exon recombination, also known as exon shuffling or domain shuffling, is an important means of new gene formation. It is observed across vertebrates, invertebrates, and in some plants such as potatoes and sunflowers. During exon recombination, exons from the same or different genes recombine and produce new exon-intron combinations, which might evolve into new genes. 
Exon shuffling follows “splice frame rules.” Each exon has three reading...