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抗原受体信号的持续时间决定了CD4+与CD8+T细胞谱系命运

K Yasutomo1, C Doyle, L Miele

  • 1Lymphocyte Biology Section, Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.

Nature
|April 13, 2000
PubMed
概括

受共同受体影响的T细胞受体信号的持续时间决定了胸细胞是否成为CD4+辅助细胞或CD8+细胞毒性T细胞. 口-1对于CD8+T细胞成熟至关重要,而不是最初的血统选择.

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