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整蛋白LFA-1与转录协激活剂JAB1相互作用,以调节AP-1活动

E Bianchi1, S Denti, A Granata

  • 1Scientific Institute San Raffaele-DIBIT, Milano, Italy. bianchi.elisabetta@hsr.it

Nature
|April 15, 2000
PubMed
概括

集成蛋白LFA-1信号调节基因表达,通过控制c-Jun联合激活剂Jun激活域结合蛋白1 (JAB1) 的核定位来调节基因表达. 这种相互作用会影响转录因子的活性,影响细胞功能.

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