平面和压缩的结肠瘤:在英国对1000次结肠镜检查进行前性研究
B J Rembacken1, T Fujii, A Cairns
1Centre for Digestive Diseases, The General Infirmary, Leeds. BJR@firstnet.co.uk
Lancet (London, England)
|April 19, 2000
概括
在结肠镜检查期间,平面和压缩的结肠直肠病变经常被忽略,尽管它们与晚期癌症有关. 训练识别这些非多聚类瘤对于早期发现结直肠癌至关重要.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 内镜检查是指内镜检查.
背景情况:
- 平和压抑的结直肠瘤最初被认为是日本独有的.
- 最近的报道表明,这些病变也存在于西方国家,尽管被认为不常见.
研究的目的:
- 调查平面和压缩结直肠病变的流行率和特征.
- 评估这些病变与发育不良和早期癌症的关联.
主要方法:
- 一项前性研究,涉及1000名连续接受常规结肠镜检查的患者.
- 欧洲结肠镜医生使用日本开发的检测平面和压缩病变的技术进行了检查.
主要成果:
- 在321个腺瘤中,36%是平坦的,0.6%是抑郁的;10%显示严重的发育不良.
- 严重发育不良或早期癌症 (杜克斯A) 的可能性随着病变大小和形态的变化而显著增加,在抑郁性病变中最高 (75%).
- 平或压抑的病变占重度发育不良或杜克斯A癌症患者的54%.
结论:
- 传统的聚焦于多性病变可能导致错过的早期结直肠瘤.
- 加强结肠镜师在识别平面和压缩病变方面的培训对于改善早期结肠直肠癌检测率至关重要.
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