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在实验性动脉样硬化中,通过慢性中性内酶抑制对功能性活跃的内甲素转化酶进行调节

J A Grantham1, J A Schirger, P W Wennberg

  • 1Cardiorenal Research Laboratory, Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN 55905, USA. grantham.aaron@mayo.edu

Circulation
|April 26, 2000
PubMed
概括

长期抑制内甲蛋白转化酶-1 (ECE-1) 与中性内酶抑制 (NEP-I) 减少了动脉瘤的形成. 这种方法中断了内分泌素系统,为心血管疾病提供了一种新的策略.

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