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Updated: Jul 4, 2026

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在确定心脏生长,发育和损伤反应中的分子表型时,cDNA微阵列的应用

P D Sehl1, J T Tai, K J Hillan

  • 1Departments of Cardiovascular Research, Genentech, Inc, South San Francisco, CA 94080, USA.

Circulation
|April 26, 2000
PubMed
概括

这项研究使用cDNA微阵列来分析老鼠心脏发育期间和心肌梗塞 (MI) 后的基因表达变化. 结果揭示了复杂的基因调节,并确定了参与心脏应激反应和发育的新型基因.

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相关概念视频

DNA Microarrays02:34

DNA Microarrays

Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...