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Updated: Jun 30, 2026

Targeted DNA Methylation Analysis by Next-generation Sequencing
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Published on: February 24, 2015

在缺乏DNMT1的人类癌细胞中,CpG甲基化得到维持

I Rhee1, K W Jair, R W Yen

  • 1The Johns Hopkins Oncology Center, and Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA.

Nature
|May 9, 2000
PubMed
概括

DNA甲基转移酶1 (DNMT1) 不仅仅负责人类癌细胞中的基因组甲基化. 其他酶保持甲基化,表明DNMT1具有区域特异性.

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