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Updated: Jan 12, 2026

Adoptive Immunotherapy of iNKT Cells in Glucose-6-Phosphate Isomerase G6PI-Induced RA Mice
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对于效应T细胞功能来说,JNK是必需的,但不是用于T细胞激活

C Dong1, D D Yang, C Tournier

  • 1Howard Hughes Medical Institute, Section of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA.

Nature
|May 16, 2000
PubMed
概括

c-Jun氨基终端激酶 (JNK) 途径对于T细胞分化至关重要,而不是T细胞初始激活. 缺乏JNK信号的小鼠显示IL-2的产生和扩散增强,但影响了效应细胞因子的产生.

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