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Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

732
Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
732

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相关实验视频

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Imaging In-Stent Restenosis: An Inexpensive, Reliable, and Rapid Preclinical Model
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在植入高活性 (32) P放射性β发射支架后,边缘缩.

R Albiero1, T Nishida, M Adamian

  • 1Emodinamica Centro Cuore Columbus, Milan, Italy. albire@micronet.it

Circulation
|June 1, 2000
PubMed
概括

较高活性 (32) P放射性支架减少了静脉内增生,但没有解决边缘复缩症. 这项研究调查了增加辐射剂量是否可以防止支架边缘的复缩.

科学领域:

  • 心血管研究研究心血管研究
  • 干预心脏病学 干预心脏病学
  • 辐射瘤学 辐射瘤学

背景情况:

  • 观察到3-12微Ci (32) P放射性支架的边缘缩率高.
  • 潜在的原因包括气球损伤和支架边缘的低辐射剂量.

研究的目的:

  • 评估是否更高活性 (12-21微Ci) (32) P放射性支架和非侵略性的植入策略可以减少边缘复缩.
  • 为了在不同活动水平之间比较静脉内静脉缩率和静脉内静脉缩率.

主要方法:

  • 对两组接受单个放射性BX支架的患者进行比较研究.
  • 组1: 3-12微Ci活性 (n=42个病变). 组2:12-21微Ci活性 (n=54个病变).
  • 在6个月的随访中评估了程序事件,临床结果和二进制复原.

主要成果:

  • 在这两组中都没有发生任何程序性事件,心肌梗塞,死亡或支架血栓.
  • 静脉内二进制复缩在1组为0%,而在2组为4% (P=NS).
  • 在2组中,静脉内新极度增生症显著降低. 在第一组中,内流静止症为38%,而在第二组中为30% (P=NS).

结论:

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  • 较高活性 (12-21 microCi) (32) P放射性支架与较低活性支架 (3-12 microCi) 相比,减少了静脉内新极致增生症.
  • 这项研究并没有解决边缘缩的问题,即使采用了非侵略性的支架植入策略.
  • 可能需要进一步的研究,以解决放射性支架应用中的边缘回.