异形性限制性心肌病的临床形象和结果
N M Ammash1, J B Seward, K R Bailey
1Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic and Mayo Foundation, Rochester, Minn. 55905, USA.
Circulation
|June 1, 2000
概括
异常限制性心肌病,一种心脏病,心室不扩张和心房扩大,预后不好. 死亡风险因素包括男性性别,年龄较大,以及晚期心力衰竭症状.
科学领域:
- 心脏病学 心脏病学
- 心血管医学 心血管医学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
背景情况:
- 异常限制性心肌病 (IRC) 是一种未被认可的心脏病.
- 它的特征是正常的腹腔大小/厚度,腹功能障碍和心房扩大.
- 未知病因与可变的缩功能.
研究的目的:
- 定义IRC的心声回声学标准.
- 评估IRC患者的临床表现和预后.
- 在IRC中确定与死亡率相关的风险因素.
主要方法:
- 对94名符合IRC (1979-1996) 严格心声学标准的患者进行了回顾性分析.
- 排除已知透性疾病或高血压的患者.
- 为生存分析和风险因素识别收集的后续数据.
主要成果:
- 该研究确定了94名IRC患者,主要是女性,平均年龄为64岁.
- 心房动 (74%) 和缩功能障碍 (16%) 是常见的.
- 50%的患者在平均68个月的随访期间死亡,死亡率明显高于预期.
结论:
- IRC,通过心声回声学定义为非扩张的,非缩的心室与心室扩张,影响不同的年龄组,但主要是老年人.
- 患者有静脉堵塞和心房动,表明预后不佳.
- 关键的死亡率预测因素包括男性性别,年龄>70,较高的NYHA类,左心房尺寸>60毫米.
相关概念视频
Myocarditis I: Introduction
647
Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
647
Cardiomyopathy I: Introduction and Classification
828
Cardiomyopathy, or CMP, is a group of diseases affecting the myocardial structure, impairing its ability to pump blood effectively. This condition can lead to arrhythmias, heart failure, or sudden cardiac death.Cardiomyopathies are classified into primary and secondary categories:Primary Cardiomyopathy refers to conditions involving only the heart muscle that are often idiopathic (of unknown cause) or genetic. They primarily affect the myocardium without the involvement of other systemic...
828
Cardiomyopathy II: Dilated Cardiomyopathy
798
Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
798
Cardiomyopathy III: Hypertrophic Cardiomyopathy
810
Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
810
Cardiomyopathy IV: Restrictive Cardiomyopathy
957
Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...
957
Cardiomyopathy V: Interprofessional Care
761
Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
761


