身体活动和女性中风风险
F B Hu1, M J Stampfer, G A Colditz
1Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115. frank.hu@channing.harvard.edu
JAMA
|June 24, 2000
概括
定期体育活动显著降低了女性总和缺血性中风的风险. 即使是像步行这样的适度运动,如果始终保持一致,也会对中风提供很大的保护.
科学领域:
- 流行病学 流行病学
- 预防医学 预防医学
- 心血管健康 心血管健康
背景情况:
- 增加体力活动与降低冠心病风险有关.
- 身体活动在中风预防中的作用需要进一步研究.
研究的目的:
- 调查身体活动水平与女性中风和其亚型的风险之间的关联.
主要方法:
- 来自护士健康研究的72,488名女性护士 (40-65岁) 的前性队列研究.
- 身体活动通过代谢等效任务 (METs) 评估,每周数小时,使用1986-1992年的问卷.
- 从基线到1994年6月1日,追踪了发生性中风病例 (总,缺血性,下关节,大脑内).
主要成果:
- 较高的体力活动水平与总中风风险有着强烈的反向关联 (趋势P=.005).
- 这种保护作用主要观察到缺血性中风 (P趋势=.003).
- 适度的活动,如步行,特别是快速步行,与总和缺血性中风的风险降低有关.
结论:
- 身体活动,包括像步行这样的中等强度运动,显著降低了总和缺血性中风的风险.
- 身体活动水平和中风风险降低之间存在剂量反应关系.
- 研究结果支持将身体活动建议纳入女性中风预防的建议.
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