在急性疾病后末期痴呆症的生存率
1Department of Geriatrics, Box 1070, Mount Sinai School of Medicine, One Gustave L. Levy Pl, New York, NY 10029, USA. sean.morrison@mssm.edu
JAMA
|June 29, 2000
概括
由于关节骨折或肺炎而住院的末期痴呆症患者的预后不佳,死亡率高. 护理应该专注于舒适,而不是对这一群体进行激进的干预.
科学领域:
- 老年病的医生 老年病的医生
- 抚慰性护理是一种缓解性护理.
- 痴呆症研究 痴呆症研究
背景情况:
- 对于患有末期痴呆症的急性病患者的预后和护理,人们对其了解甚微.
- 如果预后不好,建议强调息治疗.
研究的目的:
- 检查因骨折或肺炎住院的末期痴呆症患者的生存率.
- 为了比较这些患者接受的护理与认知完整的老年人的护理.
主要方法:
- 前性队列研究,随访期为6个月.
- 包括70岁或以上的患者,因关节骨折或肺炎住院.
- 认知完整的患者与末期痴呆症患者之间的比较.
主要成果:
- 末期痴呆症患者的六个月死亡率明显高 (53-55%),与关节骨折或肺炎后认知完整的患者 (12-13%) 相比.
- 末期痴呆症患者接受的繁重手术数量与认知完整的患者相似.
- 很少有末期痴呆症患者有记录的决定放弃维持生命的治疗,而止痛药的订单也很少出现.
结论:
- 患有晚期痴呆症和关节骨折或肺炎的患者面临着非常糟糕的预后.
- 鉴于他们的预期寿命和治疗负担有限,重点应该转向提高这一群体的舒适度.
- 建议采用息护理方法,而不是治疗干预.
更多相关视频
06:52Assessment of Dependence in Activities of Daily Living Among Older Patients in an Acute Care Unit
Published on: September 30, 2020
06:45Effect of Yi-Nao-Jie-Yu Prescription on Post-Stroke Depression in Rats using Middle Cerebral Artery Occlusion Combined with Behavioral Restraint
Published on: January 9, 2026
相关概念视频
Long-term Depression
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Long-term Depression
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Calcium Ion Concentration Mechanism
If over time, all...
Calcium Ion Concentration Mechanism
If over time, all...
Classification of Illness
The meaning of illness is individualized to each person who experiences an alteration in health. In contrast, disease is a medical term indicating a pathological change in the structure and function of the body or mind. It is a condition that has specific symptoms and boundaries.
An illness is a response to a disease in which the person's level of functioning is changed compared with a previous level. The general classification of illness includes acute and chronic.
Acute illness is severe and...
An illness is a response to a disease in which the person's level of functioning is changed compared with a previous level. The general classification of illness includes acute and chronic.
Acute illness is severe and...
Alzheimer's Disease: Treatment
Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
Rocky Mountain Spotted Fever
Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.
Alzheimer Disease l: Introduction
Alzheimer disease is a chronic, progressive, and irreversible neurodegenerative disorder and the most common cause of dementia in older adults. It leads to gradual neuronal loss, causing cognitive decline, behavioral changes, and loss of functional independence.Risk Factors and EtiologyThe disease is multifactorial. Age is the strongest risk factor, with prevalence doubling every 5 years after age 65. Genetic factors include mutations in genes such as APP, PSEN1, and PSEN2, which are associated...
