减少腹腔反应不规则与慢性心房动患者的死亡率增加有关
1Third Department of Internal Medicine, Nagoya City University Medical School, Nagoya, Japan. a.yamada@med.nagoya-cu.ac.jp
Circulation
|July 19, 2000
概括
在心房动 (AF) 期间减少腹腔响应间隔 (VRI) 不规则预测心脏死亡. 较低的VRI不规则表明AF患者的死亡风险更高,突出其预后价值.
科学领域:
- 心脏病学 心脏病学
- 生物医学工程 生物医学工程
- 临床电生理学 临床电生理学
背景情况:
- 在心房动 (AF) 中心室响应间隔 (VRI) 的变化可能与不良结果有关.
- 在AF中VRI动态的预后意义仍然不清楚.
研究的目的:
- 调查慢性AF患者临床结果的VRI可变性和不规则性的预后价值.
主要方法:
- 分析了107名慢性AF患者的24小时门诊心电图.
- 评估VRI可变性 (SD,连续差异的SD,5分钟平均值的SD) 和不规则性 (香农,符号动态,近似[ApEn(b-b),ApEn(m-m) ]).
- 在33个月的随访期间,与心脏死亡,致命性中风和全因死亡率相关的VRI测量.
主要成果:
- 减少VRI变异性和不规则性测量与心脏死亡风险增加相关.
- 在调整了喷射分数和缺血性AF后,VRI不规则度 (香农,ApEn) 独立预测了心脏死亡率.
- 较低的ApEn(b-b) 值显示,5年心脏死亡率的显著梯度 (0%对13%对43%).
结论:
- 在24小时心电图上减少VRI不规则是慢性AF心脏病死亡率的独立预测指标.
- VRI不规则性分析为管理AF患者提供了有价值的预后信息.
相关概念视频
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