定量计算机断层扫描得分的有效性和可靠性,用于预测血栓治疗前超急性中风的结果. 方面研究小组. 阿尔伯塔州中风计划 早期CT得分
P A Barber1, A M Demchuk, J Zhang
1Department of Clinical Neurosciences, University of Calgary, Canada.
Lancet (London, England)
|July 25, 2000
概括
阿尔伯塔中风计划早期CT评分 (ASPECTS) 是预测中风结果的可靠工具. 这种计算机断层扫描得分有助于识别不太可能在输血栓治疗后独立康复的患者.
科学领域:
- 神经学 神经学
- 放射学 放射学是一门学科.
- 紧急医疗 紧急医疗
背景情况:
- 计算机断层扫描 (CT) 在超急性缺血性中风治疗之前至关重要.
- 在CT上早期缺血变化的意义需要澄清.
- 阿尔伯塔中风计划早期CT评分 (ASPECTS) 是作为一个定量CT测量标准而开发的.
研究的目的:
- 评估阿尔伯塔中风计划早期CT评分 (ASPECTS) 预测急性缺血性中风的结果.
- 评估ASPECTS与症状性脑内出血和血栓消毒治疗后的功能结果之间的关联.
主要方法:
- 一项针对203名缺血性中风患者的前性研究,这些患者在症状出现后3小时内接受了高高治疗.
- 治疗前CT扫描的得分是使用ASPECTS,它将中脑动脉区分为十个区域.
- 使用后勤回归分析了ASPECTS与主要结局之间的关联:症状性脑内出血和3个月功能结局.
主要成果:
- 方面与中风严重程度相反相关 (NIH中风量表,r=-0.56,p<0.001).
- 基线方面预测了功能性结果 (p<0.001) 和症状性脑内出血 (p=0.012).
- 功能性结果的高灵敏度 (0.78) 和特异性 (0.96);观察者之间的良好一致性 (kappa 0.71-0.89).
结论:
- ASPECTS是一个简单而可靠的定量CT评分,用于急性缺血性中风.
- ASPECTS有效地识别了患者的预后不好,尽管有血栓解压疗法,但独立恢复.
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