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Murine Echocardiography of Left Atrium, Aorta, and Pulmonary Artery
Published on: February 20, 2017
身体组成和左心室缩的患病率
B Kuch1, H W Hense, B Gneiting
1Institute of Epidemiology and Social Medicine, Clinical Epidemiology Unit, University of Münster, Germany.
Circulation
|July 25, 2000
概括
对于左心室 (LV) 质量的无脂肪质量 (FFM) 正常化消除了 LV 缩 (LVH) 的性别特异性标准. 这种新方法显著改变了LVH患病率估计,特别是在肥胖个体中.
科学领域:
- 心脏病学 心脏病学
- 身体组成分析 身体成分分析
背景情况:
- 左心室 (LV) 质量正常化对于评估心脏健康至关重要.
- 使用身高或身体表面积的传统方法有局限性,包括性别特定的标准.
- 无脂肪质量 (FFM) 已成为LV质量的潜在最佳体型指数.
研究的目的:
- 评估新的基于无脂肪质量 (FFM) 的标准来诊断左心室缩 (LVH).
- 为了比较使用FFM索引与传统方法的LVH流行率.
- 评估FFM索引对不同人口子组的LVH检测的影响.
主要方法:
- 对1371名成年人 (25-74岁) 进行了心声和生物电阻分析.
- 对LVH的内部分区值是使用LV质量/FFM,LV质量/高度,LV质量/高度和LV质量/机身表面积来确定的.
- 在不同的索引方法和人口子组中,包括高血压患者和肥胖者,对LVH患病率进行了比较.
主要成果:
- LV质量/FFM产生了一个性别中立的LVH标准 (4.1g/kg).
- 根据索引方法和人口子组,LVH患病率估计有很大差异.
- 与身高 (OR2.5对5.5) 索引相比,FFM索引大大降低了肥胖女性明显的LVH风险.
结论:
- 将LV质量索引为FFM简化了LVH评估,消除了对性别特异性标准的需求.
- 基于FFM和传统的索引方法之间,LVH的患病率明显不同.
- 需要进一步的研究来确定FFM基础的LVH标准的预后意义,特别是在像肥胖者这样的特定人群中.
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