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Updated: May 5, 2026

Characterizing DNA Repair Processes at Transient and Long-lasting Double-strand DNA Breaks by Immunofluorescence Microscopy
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在DNA损伤反应中,BRCA1的功能链接和ATAXIA telangiectasia基因产物在DNA损伤反应中

S Li1, N S Ting, L Zheng

  • 1Department of Molecular Medicine/Institute of Biotechnology, University of Texas Health Science Center at San Antonio, 78245, USA.

Nature
|July 26, 2000
PubMed
概括

蛋白激酶ATM酸化CTIP,导致它在DNA受损后脱离BRCA1. 这种ATM-CtIP相互作用对于调节像GADD45.5这样的DNA修复基因至关重要.

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