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Updated: Jul 11, 2026

Single-Molecule Imaging of Nuclear Transport
12:13

Single-Molecule Imaging of Nuclear Transport

Published on: June 9, 2010

在核贩运中,FxFG核蛋白重复和进口蛋白-β之间的相互作用的结构基础

R Bayliss1, T Littlewood, M Stewart

  • 1MRC Laboratory of Molecular Biology, Cambridge, United Kingdom.

Cell
|August 10, 2000
PubMed
概括

我们确定了与核蛋白重复结合的importin-beta的晶体结构,揭示了核运输必不可少的关键相互作用. 破坏这些相互作用的突变会损害核蛋白的进口,凸显了这个复合体的功能重要性.

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Visualization of Protein-protein Interaction in Nuclear and Cytoplasmic Fractions by Co-immunoprecipitation and In Situ Proximity Ligation Assay10:05

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