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Updated: May 11, 2026

Examination of Thymic Positive and Negative Selection by Flow Cytometry
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Published on: October 8, 2012

CD3delta对T细胞受体向ERK激活和胸细胞阳性选择发出信号

P Delgado1, E Fernández, V Dave

  • 1Centro de Biología Molecular Severo Ochoa, Consejo Superior de Investigaciones Científicas, Universidad Autónoma de Madrid, Spain.

Nature
|August 10, 2000
PubMed
概括

对于T细胞受体 (TCR) 正确信号发送,T细胞发育需要CD3delta链. 缺少CD3delta会损害ERK激活和胸细胞的阳性选择,这对于成熟的T细胞分化至关重要.

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