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Updated: Jul 21, 2026

Isolation and Chemical Characterization of Lipid A from Gram-negative Bacteria
12:57

Isolation and Chemical Characterization of Lipid A from Gram-negative Bacteria

Published on: September 16, 2013

在大肠杆菌中外膜蛋白A的降解通过中性粒细胞弹性酶杀死大肠杆菌

A Belaaouaj1, K S Kim, S D Shapiro

  • 1Department of Pediatrics, Washington University School of Medicine, St. Louis, MO 63110, USA. belaaouaja@msnotes.wustl.edu

Science (New York, N.Y.)
|August 19, 2000
PubMed
概括

中性粒细胞弹性酶 (NE) 通过降解外膜蛋白A (OmpA) 来杀死大肠杆菌. 细菌或小鼠的OmpA缺乏会保护它们免受NE介导的败血症,这凸显了OmpA作为对抗格兰氏阴性细菌的主体防御的关键目标.

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