Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Hypersensitivity Reactions: Immune-Complex Reactions01:19

Hypersensitivity Reactions: Immune-Complex Reactions

127
Type III hypersensitivity reactions occur when antigen–antibody complexes form and activate the complement system. Normally, these complexes help the clearance of antigens by phagocytes and red blood cells. However, when large numbers of immune complexes are present, they can deposit in tissues—particularly in the walls of blood vessels—leading to inflammation and tissue injury. These deposits trigger complement activation and neutrophil recruitment, resulting in serum...
127
Cross-reactivity00:42

Cross-reactivity

33.8K
Overview
33.8K
Psychoneuroimmunology: Cardiovascular Disease01:27

Psychoneuroimmunology: Cardiovascular Disease

657
Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
657
Autoimmune Disorders01:29

Autoimmune Disorders

2.1K
Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
2.1K
Antigens Involved in Adaptive Immunity01:26

Antigens Involved in Adaptive Immunity

1.8K
An antigen is any substance the immune system identifies as foreign and potentially harmful to the body, prompting an immune response. Antigens have two functional properties: immunogenicity and reactivity. Immunogenicity is the ability of an antigen to stimulate a specific immune response. At the same time, reactivity describes the antigen's ability to react with the cells and antibodies produced in response to it.
Complete Antigens
Complete antigens possess both immunogenicity and...
1.8K
Antibody Actions01:26

Antibody Actions

3.5K
Antibodies, or immunoglobulins, are critical players in the immune system's arsenal against invading pathogens. Produced by B cells and plasma cells, their primary role is to detect and bind to specific antigens, molecules found on the surface of pathogens like bacteria or viruses. Beyond antigen recognition, antibodies perform several vital functions that contribute to immune defense.
Neutralization
Antibodies can bind to pathogens, preventing them from infecting host cells. This process...
3.5K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Circulating microaggregates as biomarkers for the Post-COVID syndrome.

IDCases·2024
Same author

Autoimmunity to HSP60 during diet induced obesity in mice.

International journal of obesity (2005)·2016
Same author

Is autoimmunity a side-effect of interleukin 2 production?

Immunology today·2014
Same author

Spontaneous autoimmune thyroiditis - a bird's eye view.

Immunology today·2014
Same author

Lipids and lymphocyte function.

Immunology today·2014
Same author

Pentraxin 3 (PTX3) plasma levels and carotid intima media thickness progression in the general population.

Nutrition, metabolism, and cardiovascular diseases : NMCD·2014

相关实验视频

Updated: Mar 23, 2026

Retinal and Choroidal Thickness Changes in Populations with Helicobacter pylori Infection by Swept-Source Optical Coherence Tomography
03:47

Retinal and Choroidal Thickness Changes in Populations with Helicobacter pylori Infection by Swept-Source Optical Coherence Tomography

Published on: November 1, 2024

430

感染,免疫力和动脉样硬化:对Chlamydia pneumoniae,Helicobacter pylori和cytomegalovirus的抗体与对热冲击蛋白60的免疫反应以及带或股骨动脉样硬化的免疫反应的关联.

M Mayr1, S Kiechl, J Willeit

  • 1Institute for Biomedical Aging Research, Austrian Academy of Sciences, Innsbruck.

Circulation
|August 23, 2000
PubMed
概括

长期的细菌感染,尤其是Chlamydia pneumoniae,与动脉样硬化的发展密切相关. 这项研究强调了Chlamydia pneumoniae血清阳性作为心血管风险的重要预测因素.

更多相关视频

Investigating Aortic Valve Calcification via Isolation and Culture of T Lymphocytes using Feeder Cells from Irradiated Buffy Coat
04:30

Investigating Aortic Valve Calcification via Isolation and Culture of T Lymphocytes using Feeder Cells from Irradiated Buffy Coat

Published on: February 4, 2021

3.8K
Anti-Nuclear Antibody Screening Using HEp-2 Cells
13:01

Anti-Nuclear Antibody Screening Using HEp-2 Cells

Published on: June 23, 2014

137.8K

相关实验视频

Last Updated: Mar 23, 2026

Retinal and Choroidal Thickness Changes in Populations with Helicobacter pylori Infection by Swept-Source Optical Coherence Tomography
03:47

Retinal and Choroidal Thickness Changes in Populations with Helicobacter pylori Infection by Swept-Source Optical Coherence Tomography

Published on: November 1, 2024

430
Investigating Aortic Valve Calcification via Isolation and Culture of T Lymphocytes using Feeder Cells from Irradiated Buffy Coat
04:30

Investigating Aortic Valve Calcification via Isolation and Culture of T Lymphocytes using Feeder Cells from Irradiated Buffy Coat

Published on: February 4, 2021

3.8K
Anti-Nuclear Antibody Screening Using HEp-2 Cells
13:01

Anti-Nuclear Antibody Screening Using HEp-2 Cells

Published on: June 23, 2014

137.8K

科学领域:

  • 心血管研究研究心血管研究
  • 传染性疾病 传染性疾病
  • 免疫学 免疫学 免疫学

背景情况:

  • 动脉生成是一种可能受到感染影响的炎症过程.
  • 研究特定病原体在心血管疾病中的作用至关重要.

研究的目的:

  • 评估血清阳性与冠状病毒肺炎,Helicobacter pylori,细胞巨型病毒和动脉样硬化之间的关联.
  • 评估这些感染的预测价值,以及其他风险因素,对动脉样硬化患病率和进展.

主要方法:

  • 基于人口的研究评估心血管风险因素和血清学标志物对C.肺炎,H. pylori和CMV.
  • 分析动脉样硬化在动脉和大腿动脉中的患病率和严重程度.
  • 对病变进展和与感染参数和对mHSP65.65的免疫反应的相关性进行前性监测.

主要成果:

  • 在C. pneumoniae的IgA抗体和动脉样硬化患病率/严重程度之间发现了显著的关联,独立于已确定的危险因素.
  • 在前性分析中,C. pneumoniae的血清阳性成为一个重要的风险预测因素.
  • 综合感染参数 (C. pneumoniae血清学,CRP,呼吸道感染) 显著增加了动脉样硬化病的几率比率,达到10.3.3.
  • 对H. pylori的抗体在特定情况下 (社会地位低,心动脉病变) 与血管疾病存在相关性.
  • 冠状病毒病毒阳性不是动脉样硬化患病率或发病率的重要标志物.

结论:

  • 强有力的证据支持持续性细菌感染,特别是C. pneumoniae的潜在动性作用.
  • 血清学和临床数据表明,C. pneumoniae参与了动脉动脉的产生.
  • 菌根热冲击蛋白65 (mHSP65) 的免疫反应与细菌感染之间存在相关性.