相关实验视频
Updated: Jul 8, 2026

10:08
Measuring Ascending Aortic Stiffness In Vivo in Mice Using Ultrasound
Published on: December 2, 2014
老龄化,习惯性炼和动态动脉合规性
H Tanaka1, F A Dinenno, K D Monahan
1Human Cardiovascular Research Laboratory, Department of Kinesiology and Applied Physiology, University of Colorado at Boulder, 80309-0354, USA. tanakah@colorado.edu
Circulation
|September 12, 2000
概括
定期的有氧运动有助于随着年龄的增长保持大动脉的灵活性. 耐力训练改善了中央动脉的顺应性,减少了中年和老年男性心血管疾病的风险.
科学领域:
- 心血管生理学心血管生理学
- 运动科学 运动科学
- 老年学是指老年学的学科.
背景情况:
- 降低中心动脉合规性是与年龄有关的心血管疾病的危险因素.
- 大动脉硬化是衰老的一个标志.
- 保持动脉健康对于预防心血管事件至关重要.
研究的目的:
- 调查习惯性运动对与年龄相关的中枢动脉合规性下降的影响.
- 为了比较不同年龄的男性在不同活动水平的动脉合规性.
- 评估结构化的有氧运动干预措施对动脉合规性的影响.
主要方法:
- 对151名健康男性 (18-77岁) 的横截面研究,按活动水平分类 (久坐,休,耐力训练).
- 对20名中年/老年久坐不动的男性进行了干预性研究,他们接受了为期3个月的有氧运动计划.
- 使用B模式超声波和平面化度测量中央动脉合规性.
主要成果:
- 在所有组中,随着年龄的增长,中枢动脉的合规性下降.
- 耐力训练的男性表现出比久坐/休活动的男性高出20-35%的动脉合规性.
- 在以前久坐不动的男性中,有氧运动干预显著增加了动脉合规性.
结论:
- 定期的有氧耐力运动减轻了与年龄相关的中枢动脉合规性的减少.
- 运动可以恢复静止中年和老年男性的动脉顺应.
- 改善动脉顺应可能是通过习惯性炼降低心血管疾病风险的关键机制.
更多相关视频
相关概念视频
Assessment of blood pressure in brachial artery(two-step method)
Measuring blood pressure is a fundamental skill in healthcare that aids in diagnosing and monitoring hypertension and other cardiovascular conditions. An aneroid sphygmomanometer, commonly used in clinical settings, offers a manual and precise method for blood pressure measurement. The technique for using this instrument involves specific steps that must be carefully executed to ensure accuracy. The following detailed description outlines a two-step technique for assessing blood pressure using...
Pre-Procedural Guidelines for Assessing Blood Pressure
Accurate blood pressure assessment is crucial for diagnosing and managing various health conditions. To ensure the reliability of these measurements, healthcare professionals must adhere to standardized pre-procedural guidelines. These guidelines enhance patient safety and improve the overall quality of healthcare. The following steps are essential for obtaining accurate and consistent blood pressure readings, from using the appropriate tools to ensuring effective communication with the patient.
Exercise and Cardiac Output
Regular physical activity is essential for maintaining cardiovascular health, with aerobic exercises being particularly effective. According to the American Heart Association, 150 minutes of moderate to intense aerobic exercise per week is recommended for a healthy heart. Aerobic activities may include brisk walking, running, bicycling, cross-country skiing, and swimming, ideally performed three to five times per week.
Sustained exercise increases the muscles' oxygen demand, which can be met...
Sustained exercise increases the muscles' oxygen demand, which can be met...
Autoregulation of Blood Flow
Autoregulation mechanisms are characterized by their inherent capacity for self-regulation without necessitating specific nervous stimulation or endocrine control. These mechanisms facilitate the adjustment of blood flow and, therefore, perfusion specific to each tissue region. This self-regulation encompasses chemical signals and myogenic controls.
Chemical Signaling in Autoregulation
Chemical signaling operates at the precapillary sphincter level, inciting either contraction or relaxation.
Chemical Signaling in Autoregulation
Chemical signaling operates at the precapillary sphincter level, inciting either contraction or relaxation.
Exercise and Cardiovascular Response
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...

