全谷物消费和女性缺血性中风风险:一项前性研究
S Liu1, J E Manson, M J Stampfer
1Division of Preventive Medicine, Bringham and Women's Hospital, 900 Commonwealth Ave E, Boston, MA 02215, USA. simin.liu@channing.harvard.edu
JAMA
|September 23, 2000
概括
较高的全谷物摄入量与女性缺血性中风风险降低有关. 这些发现支持将全谷物纳入饮食中,以预防心血管疾病.
科学领域:
- 流行病学 流行病学
- 营养科学 营养科学
- 心血管健康 心血管健康
背景情况:
- 饮食建议经常建议增加谷物产品的摄入量,以预防心血管疾病 (CVD).
- 然而,关于全谷物消费与缺血性中风风险之间的具体关系的前性数据有限,特别是在女性中.
研究的目的:
- 调查假设,更多的全谷物消费与女性缺血性中风风险较低有关.
主要方法:
- 一项前性队列研究,涉及来自护士健康研究的75,521名美国妇女 (38-63岁).
- 从1984年到1994年,参与者填写了详细的食物频率问卷 (FFQ),并在12年内进行了跟踪.
- 缺血性中风发生率通过医疗记录得到证实,并通过五分之一的全谷物摄入量进行分析.
主要成果:
- 在随访期间 (861,900人年),发现了352例缺血性中风病例.
- 在全谷物摄入量和缺血性中风风险之间观察到一个反向关联 (P=.003趋势).
- 在调整吸烟,心血管疾病风险因素,和脂肪和反式脂肪酸摄入量后,这种关联仍然存在.
结论:
- 较高的全谷物食品摄入量与女性缺血性中风风险降低有关.
- 这种关系独立于已确定的心血管疾病风险因素.
- 这些发现支持全谷物在减轻缺血性中风风险方面的潜在作用.
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