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Updated: Jun 12, 2026

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Published on: November 2, 2018

在A20缺乏的小鼠中,未能调节TNF诱导的NF-kappaB和细胞死亡反应

E G Lee1, D L Boone, S Chai

  • 1Department of Medicine, The University of Chicago, 5841 South Maryland Avenue, MC 6084, Chicago, IL 60637, USA.

Science (New York, N.Y.)
|September 29, 2000
PubMed
概括

A20蛋白通过阻止瘤亡因子 (TNF) 诱导的核因子kappaB (NF-kappaB) 反应来限制炎症. 缺乏A20的小鼠表现出严重的炎症和细胞死亡的增加,突出A20

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