相关实验视频
Updated: Jul 9, 2026

13:39
Optical Trapping of Nanoparticles
Published on: January 15, 2013
概括
高含量和离子体 (A23187) 阻止了淡水的状毛. 这一发现支持了增加内部触发这些生物体的状体停止的理论.
科学领域:
- 海洋生物学 海洋生物学
- 细胞生理学 细胞生理学
- 无脊椎动物动物学
背景情况:
- 毛对于水生生物的呼吸和养至关重要.
- 淡水的侧侧毛的超时节律促进了水的流动.
- 离子是众所周知的各种细胞过程的调节者,包括运动性.
研究的目的:
- 为了研究在淡水的状功能中的作用.
- 为了确定是否升高的细胞内水平可以诱导状动脉停止.
主要方法:
- 隔离的鱼状组织的透,含有不同度的化和离子体A23187.
- 在不同的化学条件下观察状拍打模式.
- 在离子体被移除后,评估毛活动的恢复.
主要成果:
- 输入6.25-12.5mM和10(-5) M A23187导致侧面毛的停止,毛向前.
- 无论是单独的,单独的离子体,还是单价离子体都不会诱导膜停止.
- 离子体被移除后,纤维细胞活动恢复,恢复率因阴离子 (KCl > CaCl2 > NaCl) 不同.
结论:
- 实验结果强烈支持这样一个假设,即细胞内度局部增加是淡水贝的直接原因.
- 这项研究阐明了一种特定的依赖的机制,调节双动物的状功能.
相关概念视频
Receptor-mediated Endocytosis
Overview
Intracellular Movement of Viruses and Bacteria
Intracellular bacteria and viruses often comprise a group of highly infectious pathogens that can cause several diseases. Bacterial pathogens include those belonging to the genus Rickettsia responsible for conditions such as rocky mountain spotted fever and the Mediterranean spotted fever; Chlamydia, a genus responsible for a sexually transmitted disease; Coxiella burnetii, an agent responsible for Q fever. Viral pathogens include vaccinia—a poxvirus, and herpes simplex virus—a virus that...
Pinching-off of Coated Vesicles
Vesicle budding is orchestrated by distinct cytosolic proteins such as adaptor proteins, coat proteins, and GTPases. To initiate vesicle budding, membrane-bending proteins containing crescent-shaped BAR domains bind to the lipid heads in the bilayer and distort the membrane to form a protein-coated vesicle bud. Adaptors proteins such as AP2 for clathrin-coated vesicles can nucleate on the deformed membrane. Finally, coat proteins such as clathrin or COPI and COPII assemble into a coat forming...
Mechanism of Filopodia Formation
Filopodia are thin, actin-rich cellular protrusions that play an important role in many fundamental cellular functions. They vary in their occurrence, length, and positioning in different cell types, suggesting their diverse roles.
Their main function is to guide migrating cells during normal tissue morphogenesis or cancer metastasis by recognizing and making initial contacts with the extracellular matrix. However, they can also act as stationary cell anchors or help to establish communication...
Their main function is to guide migrating cells during normal tissue morphogenesis or cancer metastasis by recognizing and making initial contacts with the extracellular matrix. However, they can also act as stationary cell anchors or help to establish communication...
Mechanism of Lamellipodia Formation
Cells migrating in response to external stimuli form lamellipodia, which are thin membrane protrusions supported by a mesh of linked, branched, or unbranched actin filaments. These actin filaments interact with myosin motor proteins, creating the dynamic actomyosin complex within the cytoskeleton. Contractility, or the ability to generate contractile stress, is inherent to the actomyosin complex. It helps cells detect the stiffness of the surrounding ECM and exert contractile force for...
Atomic Nuclei: Nuclear Relaxation Processes
In the absence of an external magnetic field, nuclear spin states are degenerate and randomly oriented. When a magnetic field is applied, the spins begin to precess and orient themselves along (lower energy) or against (higher energy) the direction of the field. At equilibrium, a slight excess population of spins exists in the lower energy state. Because the direction of the magnetic field is fixed as the z-axis, the precessing magnetic moments are randomly oriented around the z-axis. This...

