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急性和慢性压力在儿童喘发作中的作用
S Sandberg1, J Y Paton, S Ahola
1Hospital for Children and Adolescents, University of Helsinki, Finland.
Lancet (London, England)
|October 21, 2000
概括
严重的生活事件可以引发儿童的喘发作. 这种风险更高,如果孩子也经历了持续的慢性压力,那么它会更快发生.
科学领域:
- 儿科肺病学 儿科肺病学
- 精神病体医学是一种精神病体医学.
- 儿童心理学 儿童心理学
背景情况:
- 高压力水平与遗传倾向儿童的喘发作和增加的发病率有关.
- 现有的研究表明,压力和喘严重程度之间存在关联.
研究的目的:
- 调查是否有压力经历在患有喘的儿童中导致新的喘恶化.
- 量化严重生活事件和慢性压力因素对喘发作的影响.
主要方法:
- 对儿童喘患者进行未来18个月的随访.
- 通过日记和峰值流量测量进行持续的喘监测.
- 重复采访评估生活事件和心理社会经验,包括严重的负面生活事件和慢性压力因素.
主要成果:
- 严重的生活事件显著增加了喘发作风险,特别是在事件发生后2-6周 (或1.71-2.17)
- 当严重事件与高慢性压力 (OR 2.98) 相吻合时,风险被放大和加速 (在2周内).
- 诸如女性性别,基线严重程度,频繁发作,季节和父母吸烟等因素增加了恶化风险;社会阶级和慢性压力与整体发作频率没有直接相关.
结论:
- 严重的负面生活事件在几周内增加了儿童喘发作的风险.
- 多种慢性压力因素的存在加大了这种风险,并缩短了喘恶化的潜伏期.
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