高血压与大动脉动脉样硬化的独立关联:基于人口的研究
Y Agmon1, B K Khandheria, I Meissner
1Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA.
Circulation
|October 25, 2000
概括
高血压与大动脉动脉样硬化有关. 这包括复杂的斑块积累,突出了血压管理对于预防中风的重要性.
科学领域:
- 心血管研究的心血管研究.
- 公共卫生 公共卫生
背景情况:
- 胸前动脉的动脉样硬化是已知的中风风险因素.
- 高血压是中风的主要危险因素,但其与大动脉动脉样硬化在一般人群中的联系尚不清楚.
研究的目的:
- 在一般人口样本中确定高血压和大动脉动脉硬化之间的关联.
- 为了调查血压是否与复杂的大动脉动脉样硬化有关.
主要方法:
- 581名45岁以上的成年人进行过食道回声心电图,来自明尼苏达州奥姆斯特德县.
- 通过办公室测量和24小时门诊监测来评估血压.
- 多重逻辑回归用于分析关联,根据年龄和吸烟进行调整.
主要成果:
- 年龄和吸烟独立地与任何复杂的大动脉动脉样硬化有关.
- 缩和脉冲压,但不是腹缩,与大动脉动脉样硬化有关.
- 较高的门诊系统性血压和高血压治疗与复杂的大动脉动脉样硬化的几率增加相关.
结论:
- 高血压独立地与大动脉动脉样硬化有关.
- 高血压与更复杂的动脉动脉样硬化的形式有关.
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