脊椎动物尾肌肉的进化起源
1Comparative and Developmental Genetics Section, Medical Research Council, Western General Hospital, Edinburgh, UK.
Nature
|November 18, 2000
概括
四足动物的四肢肌肉是从类似斑马鱼的迁徙细胞进化而来的,而不是从狗鱼中看到的直接延伸. 这表明,四肢肌肉形成的遗传基础早于萨尔科普特里吉亚辐射.
科学领域:
- 进化生物学是进化的生物学.
- 发育生物学是发展生物学.
- 比较解剖学的比较解剖学.
背景情况:
- 陆地四足动物使用四肢肌肉发展了新的运动运动策略,与大多数使用轴向肌肉的鱼不同.
- 化石记录详细介绍了四足动物尾骨的演变,但没有详细介绍四肢肌肉的起源.
研究的目的:
- 研究现存鱼类物种中翅膀肌肉的发育起源.
- 为了将这些起源与已知的四足动物四肢肌肉的发展进行比较.
- 推断控制四足肢肌肉形成的遗传机制的进化时间.
主要方法:
- 斑马鱼 (teleost) 和狗鱼 (chondrichthyan) 胚胎的翅膀肌肉发育的比较分析.
- 检查肌肉前体细胞的细胞起源和形态遗传途径.
主要成果:
- 斑马鱼的翅膀肌肉起源于迁徙的介质细胞前体细胞,与四足动物四肢肌肉前体共享分子和形态遗传特征.
- 狗鱼胚胎通过直接的上皮索米特延伸,一种更原始的机制来发展翅膀肌肉.
结论:
- 四足动物四肢肌肉形成的遗传机制可能是在萨科普特里亚斯辐射之前演变的.
- 这一发现揭示了从翅膀到四肢发育的进化过渡.
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