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Updated: Jun 30, 2026

Mechanistic Insight into the Development of TNBS-Mediated Intestinal Fibrosis and Evaluating the Inhibitory Effects of Rapamycin
10:21

Mechanistic Insight into the Development of TNBS-Mediated Intestinal Fibrosis and Evaluating the Inhibitory Effects of Rapamycin

Published on: September 12, 2019

在克罗恩病治疗因弗力西马布失效的机制

S Nikolaus1, A Raedler, T Kühbacker

  • 1Christian-Albrechts-University, First Department of Medicine, Kiel, Germany.

Lancet (London, England)
|November 18, 2000
PubMed
概括

在大多数患者中,Infliximab最初改善了克罗恩病的症状,但在症状复发之前,许多人因为免疫标记物如瘤缩因子-α (TNF-alpha) 和核因子kappa B (NFkappaB) 被重新激活而复发.

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