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Protective Efficacy and Pulmonary Immune Response Following Subcutaneous and Intranasal BCG Administration in Mice
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Published on: September 19, 2016

鼠类白血病的BCG抑制:局部抑制和全身瘤免疫需要不同的剂量

G L Bartlett, D M Purnell, J W Kreider

    Science (New York, N.Y.)
    |January 23, 1976
    PubMed
    概括

    最佳的菌卡尔梅特-盖林 (BCG) 和瘤细胞比率用于立即抑制瘤,阻碍了对LSTRA小鼠白血病的长期免疫力的发展. 这表明,有效的癌症免疫疗法需要一个微妙的平衡.

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    Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.