在缺血性心肌病中进行心脏梗塞排除手术后,对左心室功能进行实时三维回声心脏学研究
J X Qin1, T Shiota, P M McCarthy
1Department of Cardiology, Thoracic and Cardiovascular Surgery and Kaufman Center for Heart Failure, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.
Circulation
|November 18, 2000
概括
心脏梗塞排除手术显著减少左心室体积和改善射出分数,导致更好的心脏功能和患者的结果. 实时3D心声回声学有效地监测了手术后的这些变化.
科学领域:
- 心脏病学 心脏病学
- 医疗成像医学成像
- 手术创新 在外科创新.
背景情况:
- 缺血性心肌病在左心室 (LV) 重建方面存在挑战.
- 准确的体积量化对于评估心脏病排除 (IE) 手术结果至关重要.
- 手术后复杂的几何变化需要精确的测量技术.
研究的目的:
- 评估实时3D心声回声学 (RT3DE) 在量化IE手术后LV体积和功能的变化方面的有效性.
- 为了将RT3DE发现与接受LV重建的患者的临床结果相关联.
主要方法:
- 在30名患者中,在IE手术前后进行了心RT3DE.
- 在22名患者中进行了跨胸部RT3DE随访.
- 用重复测量ANOVA和斯皮尔曼相关性进行统计分析.
主要成果:
- IE手术导致LV终端-透气和终端-缩体积指数显著下降 (P<0.05).
- LV 喷射分数显著增加,并在手术后维持 (P<0.05).
- 观察到前进中风体积和纽约心脏协会功能类的改善 (分别P<0.005和P<0.0001).
结论:
- RT3DE是复杂的LV重建后LV变化的定量评估的一个有价值的工具.
- 减少LV体积和改善IE手术后的射出分数与减少LV壁应力相关,并预测症状改善.
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