住院炼训练对冠状动脉疾病患者的鼓动反射灵敏度和心率变异性的影响:一项随机对照研究
F Iellamo1, J M Legramante, M Massaro
1Dipartimento di Medicina Interna, Centro di Riabilitazione Madonna della Letizia, Università di Roma, Tor Vergata, Rome, Italy. iellamo@med.uniroma2.it
Circulation
|November 22, 2000
概括
运动训练显著改善了冠状动脉疾病患者的巴罗反射灵敏度 (BRS) 和心率变化. 这种心脏自主功能的增强支持运动作为缺血性心脏病的二次预防策略的关键组成部分.
科学领域:
- 心脏病学 心脏病学
- 运动生理学 运动生理学
- 自主神经科学 自主神经科学
背景情况:
- 肌肉性心脏缺血和心脏病发作降低了巴罗反射灵敏度 (BRS),这是肌肉性心脏病发作 (MI) 后心脏事件的预测因素.
- 抑郁的BRS表明自主心血管调节受损.
研究的目的:
- 为了研究运动训练对冠状动脉疾病 (CAD) 患者的巴罗反射灵敏度 (BRS) 的影响.
主要方法:
- 97名男性患者有或没有先前的MI被随机分为训练有素 (TR) 或未训练有素 (UTR) 组.
- TR组接受了为期2周的强度炼计划 (每天2次,每周6天) 在85%HRmax.
- 在基线和研究结束时通过RR间隔标准偏差 (RRSD) 测量了BRS和心率变化 (HRV).
主要成果:
- 在TR组中,运动训练显著增加了BRS (3.0到5.3毫秒/mmHg) 和RRSD (18.7到23.6毫秒) (分别P<0.001和P<0.01).
- 在UTR组中没有观察到BRS或RRSD的显著变化.
- 在TR组中,在有或没有先前的MI的患者中,BRS和RRSD的改善得到了观察.
结论:
- 在冠状动脉疾病患者中,运动训练有效地增强了BRS和HRV.
- 通过运动训练改善自主功能可能有助于二次预防缺血性心脏病.
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