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β-arrestin 2:一种受体调节的MAPK支架,用于JNK3的激活

P H McDonald1, C W Chow, W E Miller

  • 1Howard Hughes Medical Institute and Department of Medicine, Duke University Medical Center, Box 3821, Durham, NC 27710, USA.

Science (New York, N.Y.)
|November 25, 2000
PubMed
概括

β-arrestin 2作为支架蛋白,与c-Jun氨基终端激酶3 (JNK3) 和其激活剂结合. 这种相互作用控制了JNK3的活性和局部化,以应对G蛋白结合受体 (GPCR) 刺激.

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