感染性内心炎的危险因素:口腔卫生和非口腔暴露
B L Strom1, E Abrutyn, J A Berlin
1Department of Biostatistics and Epidemiology and Center for Clinical Epidemiology and Biostatistics, Division of General Internal Medicine, University of Pennsylvania, Philadelpha 19104-6021, USA. Bstrom@cceb.med.upenn.edu
Circulation
|January 11, 2000
概括
传染性内心炎 (IE) 与严重的病和糖尿病有关,而不是常见的医疗程序. 每天用牙线清洁可能会略微降低牙科菌群的IE风险.
科学领域:
- 心脏病学 心脏病学
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- 感染性内心炎 (IE) 的危险因素尚未得到充分了解.
- 识别特定的风险因素对于预防和管理至关重要.
研究的目的:
- 调查各种疾病,手术和社区感染性内心炎 (IE) 之间的关联.
- 在以人口为基础的研究中识别IE可修改和不可修改的风险因素.
主要方法:
- 从1988年到1990年,在费城地区进行了一项基于人口的病例控制研究.
- 社区获得的IE病例 (不包括静脉注射药物使用) 与匹配的社区居民进行了比较.
- 风险因素通过采访进行评估,并通过专家医疗记录审查确认.
主要成果:
- 严重的病 (OR=16.9) 和糖尿病 (OR=2.7) 与IE风险增加有显著的关联.
- 皮肤菌群引起的IE患者的先前静脉注射液体使用率 (OR=6.7) 和皮肤感染率较高.
- 没有发现IE与最近的肺,肠道,心脏或GU手术或手术之间存在关联.
- 与每天不用牙线刷牙的牙患者相比,没有牙的牙菌群对IE的风险较低.
结论:
- 传染性内心炎 (IE) 与特定的潜在疾病有关,如严重的病和糖尿病.
- 最近的医疗或牙科手术在本研究中没有被确定为重大风险因素.
- 每天使用牙线显示IE风险降低了边界线,这表明了潜在的预防措施.
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