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Stimulation of Cytoplasmic DNA Sensing Pathways In Vitro and In Vivo
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一个类似Toll的受体识别了细菌DNA.

H Hemmi1, O Takeuchi, T Kawai

  • 1Department of Host Defense, Research Institute for Microbial Diseases, Osaka University and Core Research for Evolutional Science and Technology, Japan Science and Technology Corporation, Suita.

Nature
|December 29, 2000
PubMed
概括

含有CpG基因的细菌DNA可以激活免疫细胞. 研究人员发现,Toll-like受体9 (TLR9) 调解了这种反应,突出了它在区分外来与自身DNA中的作用.

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