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Updated: Jun 25, 2026

A Simplified System for Evaluating Cell Mechanosensing and Durotaxis In Vitro
09:50

A Simplified System for Evaluating Cell Mechanosensing and Durotaxis In Vitro

Published on: August 27, 2015

通过质细胞控制突触数量

E M Ullian1, S K Sapperstein, K S Christopherson

  • 1Stanford University School of Medicine, Department of Neurobiology, Fairchild Science Building, Stanford, CA 94305-5125, USA. emu@stanford.edu

Science (New York, N.Y.)
|February 7, 2001
PubMed
概括

质细胞,特别是星体细胞,对于大脑功能至关重要,诱导和稳定突触. 它们的缺失导致突触不成熟和较少,突出显示它们在神经发育和可塑性方面的重要作用.

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Cell-matrix's Response to Mechanical Forces01:13

Cell-matrix's Response to Mechanical Forces

In animal cells, the extracellular matrix allows cells within tissues to withstand external stresses and transmits signals from the outside of the cell to the inside. The extracellular matrix is extensive, and its composition varies between different types of tissues. For example, the reticular fibers and ground substance make up the ECM in loose connective tissue, while collagen and bone minerals make up the ECM of bone tissue. 
Anchoring junctions mechanically attach a cell to the...